Which client statement during assessment may suggest marijuana use?

The statement indicating that "My eyes have looked bloodshot lately" is associated with marijuana use because one of the well-known physiological effects of marijuana consumption is the dilation of blood vessels, which can lead to bloodshot or red eyes. This occurs due to the presence of cannabinoids that affect blood flow within the eyes, causing them to appear more red than usual.

The other statements do not directly align with the typical signs of marijuana use. A decrease in appetite, weight loss, and feelings of being off-balance can be linked to a variety of health issues or substance uses but are not specific indicators of marijuana use. In particular, marijuana is often associated with increased appetite rather than decreased, making the bloodshot eyes the more telling symptom in this context.